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Two matrix factorisation methods to solve drug-target interaction problem

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Matrix Factorisation for Drug-Target Interactions

Code is part of a group project for a task set by AstraZeneca

Includes two models:

  • Base Matrix Factorisation which is the standard matrix factorisation model using stochastic gradient descent
  • Matrix Factorisation with similarity matrices, which uses the chemical similarites of the drugs and targets to better approximate a drug-target interaction

Institution: University of Sheffield

Project Supervisors: Haiping Lu and Peizhen Bai

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Two matrix factorisation methods to solve drug-target interaction problem

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