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cmpo.obo
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format-version: 1.2
data-version: http://www.ebi.ac.uk/cmpo/releases/2017-12-19/cmpo.obo
subsetdef: cmpo "CMPO subset"
subsetdef: goantislim_grouping "Grouping classes that can be excluded"
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_do_not_manually_annotate "Term not to be used for direct manual annotation"
subsetdef: goslim_aspergillus "Aspergillus GO slim"
subsetdef: goslim_candida "Candida GO slim"
subsetdef: goslim_chembl "ChEMBL protein targets summary"
subsetdef: goslim_generic "Generic GO slim"
subsetdef: goslim_goa "GOA and proteome slim"
subsetdef: goslim_metagenomics "Metagenomics GO slim"
subsetdef: goslim_pir "PIR GO slim"
subsetdef: goslim_plant "Plant GO slim"
subsetdef: goslim_pombe "Fission yeast GO slim"
subsetdef: goslim_synapse "synapse GO slim"
subsetdef: goslim_virus "Viral GO slim"
subsetdef: goslim_yeast "Yeast GO slim"
subsetdef: gosubset_prok "Prokaryotic GO subset"
subsetdef: mf_needs_review "Catalytic activity terms in need of attention"
subsetdef: termgenie_unvetted "Terms created by TermGenie that do not follow a template and require additional vetting by editors"
subsetdef: virus_checked "Viral overhaul terms"
synonymtypedef: systematic_synonym "Systematic synonym" EXACT
ontology: http://www.ebi.ac.uk/cmpo/cmpo.obo
owl-axioms: Prefix(owl:=<http://www.w3.org/2002/07/owl#>)\nPrefix(rdf:=<http://www.w3.org/1999/02/22-rdf-syntax-ns#>)\nPrefix(xml:=<http://www.w3.org/XML/1998/namespace>)\nPrefix(xsd:=<http://www.w3.org/2001/XMLSchema#>)\nPrefix(rdfs:=<http://www.w3.org/2000/01/rdf-schema#>)\n\n\nOntology(\nDeclaration(AnnotationProperty(<http://www.geneontology.org/formats/oboInOwl#id>))\n\n\nAnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/BFO_0000050> \"part_of\"^^xsd:string)\n)
[Term]
id: CMPO:0000002
name: cell population phenotype
def: "A quality that that inheres in a population of cells" []
subset: cmpo
is_a: CMPO:0000003 ! cellular phenotype
property_value: prefLabel "cell population phenotype" xsd:string
[Term]
id: CMPO:0000003
name: cellular phenotype
def: "A quality that inheres in or specifically depends on a cellular process, a cell population, a whole cell or a subcellular structure." []
subset: cmpo
property_value: prefLabel "cellular phenotype" xsd:string
[Term]
id: CMPO:0000005
name: cell morphology phenotype
def: "A collection of qualities that inhere in the whole cell relating to the cell's shape, size or structure" []
subset: cmpo
is_a: CMPO:0000258 ! single cell phenotype
is_a: CMPO:0000303 ! cell component morphology phenotype
property_value: prefLabel "cell morphology" xsd:string
[Term]
id: CMPO:0000007
name: cell process phenotype
def: "A quality that inheres in a cellular process" []
subset: cmpo
synonym: "cell physiology phenotype" EXACT []
is_a: CMPO:0000003 ! cellular phenotype
property_value: prefLabel "cell process phenotype" xsd:string
[Term]
id: CMPO:0000008
name: cell component number phenotype
def: "An increase or decrease in the number of specified components within a cell" []
subset: cmpo
is_a: CMPO:0000258 ! single cell phenotype
property_value: prefLabel "cell component number" xsd:string
[Term]
id: CMPO:0000010
name: cell component size phenotype
def: "A collection of size qualities that inhere in a cellular component" []
subset: cmpo
is_a: CMPO:0000303 ! cell component morphology phenotype
property_value: prefLabel "cell component size" xsd:string
[Term]
id: CMPO:0000011
name: cell component shape phenotype
def: "A collection of shape qualities that inhere in a cellular component" []
subset: cmpo
is_a: CMPO:0000303 ! cell component morphology phenotype
property_value: prefLabel "cell component shape" xsd:string
[Term]
id: CMPO:0000012
name: cell component structure phenotype
def: "A collection of structure qualities that inhere in a cellular component" []
subset: cmpo
is_a: CMPO:0000303 ! cell component morphology phenotype
property_value: prefLabel "cell component structure" xsd:string
[Term]
id: CMPO:0000013
name: cell viability phenotype
def: "A phenotype relating to the ability of a cell survive or to develop normally" []
subset: cmpo
is_a: CMPO:0000258 ! single cell phenotype
property_value: prefLabel "cell viability" xsd:string
[Term]
id: CMPO:0000014
name: viable cell phenotype
def: "A cell phenotype where the cell is viable" []
subset: cmpo
is_a: CMPO:0000013 ! cell viability phenotype
property_value: prefLabel "viable cell" xsd:string
[Term]
id: CMPO:0000015
name: inviable cell phenotype
def: "A cell phenotype where the cell is not viable" []
subset: cmpo
is_a: CMPO:0000013 ! cell viability phenotype
property_value: prefLabel "inviable cell" xsd:string
[Term]
id: CMPO:0000016
name: cell nucleation phenotype
def: "A nucleation quality that inheres in the whole cell" []
subset: cmpo
is_a: CMPO:0000258 ! single cell phenotype
property_value: prefLabel "cell nucleation" xsd:string
[Term]
id: CMPO:0000017
name: mononuclear cell phenotype
subset: cmpo
is_a: CMPO:0000016 ! cell nucleation phenotype
property_value: prefLabel "mononuclear cell" xsd:string
[Term]
id: CMPO:0000018
name: multinucleated cell phenotype
def: "A multinucleate quality that inheres in a cell" []
subset: cmpo
synonym: "polynuclear cell" EXACT []
is_a: CMPO:0000016 ! cell nucleation phenotype
property_value: prefLabel "multinucleated cell" xsd:string
[Term]
id: CMPO:0000020
name: cytoskeletal phenotype
def: "A collection of qualities that inhere in any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice." []
subset: cmpo
is_a: CMPO:0000150 ! organelle phenotype
property_value: prefLabel "cytoskeletal phenotype" xsd:string
[Term]
id: CMPO:0000021
name: endoplasmic reticulum phenotype
def: "A collection of qualities that inhere in any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae." []
subset: cmpo
is_a: CMPO:0000150 ! organelle phenotype
property_value: prefLabel "endoplasmic reticulum phenotype" xsd:string
[Term]
id: CMPO:0000022
name: golgi phenotype
def: "A collection of qualities that inhere in any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack" []
subset: cmpo
is_a: CMPO:0000150 ! organelle phenotype
property_value: prefLabel "golgi phenotype" xsd:string
[Term]
id: CMPO:0000023
name: mitochondrion phenotype
def: "A collection of qualities that inhere in any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells." []
subset: cmpo
synonym: "mitochondrial part phenotype" EXACT []
is_a: CMPO:0000150 ! organelle phenotype
property_value: prefLabel "mitochondrion phenotype" xsd:string
[Term]
id: CMPO:0000024
name: nuclear phenotype
def: "A collection of qualities that inhere in any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated." []
subset: cmpo
is_a: CMPO:0000150 ! organelle phenotype
property_value: prefLabel "nuclear phenotype" xsd:string
[Term]
id: CMPO:0000026
name: organelle shape phenotype
def: "A collection of qualities that inhere in a cellular organelle relating to the organelle's shape" []
subset: cmpo
is_a: CMPO:0000011 ! cell component shape phenotype
property_value: prefLabel "organelle shape" xsd:string
[Term]
id: CMPO:0000027
name: nucleus shape phenotype
def: "A collection of qualities that inhere in the nucleus relating to the ratios of distances between its features (points, edges, surfaces and also holes etc)." []
subset: cmpo
synonym: "nuclear shape" EXACT []
is_a: CMPO:0000026 ! organelle shape phenotype
is_a: CMPO:0000249 ! nuclear morphology phenotype
[Term]
id: CMPO:0000028
name: cell adhesion phenotype
def: "A phenotype where the attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules is observed" []
subset: cmpo
is_a: CMPO:0000007 ! cell process phenotype
property_value: prefLabel "cell adhesion phenotype" xsd:string
[Term]
id: CMPO:0000029
name: cell cycle phenotype
def: "A collection of qualities that inhere the cell cycle" []
subset: cmpo
is_a: CMPO:0000007 ! cell process phenotype
property_value: prefLabel "cell cycle phenotype" xsd:string
[Term]
id: CMPO:0000030
name: cell death phenotype
def: "A phenotype where the cell death process process is observed" []
subset: cmpo
is_a: CMPO:0000007 ! cell process phenotype
property_value: IAO:0000119 PMID:20360735 xsd:string
property_value: prefLabel "cell death phenotype" xsd:string
[Term]
id: CMPO:0000032
name: cell membrane organisation phenotype
def: "A phenotype observation of a process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." []
subset: cmpo
is_a: CMPO:0000007 ! cell process phenotype
property_value: prefLabel "cell membrane organisation phenotype" xsd:string
[Term]
id: CMPO:0000033
name: cell migration phenotype
def: "A phenotype of a cell involving its translation from one location to another" []
subset: cmpo
is_a: CMPO:0000244 ! cell component movement phenotype
property_value: IAO:0000119 PMID:20360735 xsd:string
property_value: prefLabel "cell migration phenotype" xsd:string
[Term]
id: CMPO:0000035
name: cell growth phenotype
def: "A phenotype observation of the process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." []
subset: cmpo
is_a: CMPO:0000007 ! cell process phenotype
property_value: prefLabel "cell growth phenotype" xsd:string
[Term]
id: CMPO:0000036
name: chromosome segregation phenotype
def: "A phenotype observation of the process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the alignment of chromosomes at the metaphase plate, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." []
subset: cmpo
is_a: CMPO:0000007 ! cell process phenotype
property_value: prefLabel "chromosome segregation phenotype" xsd:string
[Term]
id: CMPO:0000037
name: metabolic process phenotype
def: "A phenotype observation of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." []
subset: cmpo
is_a: CMPO:0000007 ! cell process phenotype
property_value: prefLabel "metabolic process phenotype" xsd:string
[Term]
id: CMPO:0000038
name: organelle localization phenotype
def: "A phenotype observations where any process in which an organelle is transported to, and/or maintained in, a specific location." []
subset: cmpo
is_a: CMPO:0000356 ! cell component localization phenotype
property_value: prefLabel "organelle localization phenotype" xsd:string
[Term]
id: CMPO:0000039
name: regulation of metabolic process phenotype
def: "A phenotype observation where a process modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." []
subset: cmpo
is_a: CMPO:0000334 ! regulation of process phenotype
property_value: prefLabel "regulation of metabolic process phenotype" xsd:string
[Term]
id: CMPO:0000040
name: regulation of signal transduction phenotype
def: "A phenotype observation of a process that modulates the frequency, rate or extent of signal transduction." []
subset: cmpo
is_a: CMPO:0000334 ! regulation of process phenotype
property_value: prefLabel "regulation of signal transduction phenotype" xsd:string
[Term]
id: CMPO:0000041
name: transport phenotype
def: "A phenotype observation of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore." []
subset: cmpo
is_a: CMPO:0000356 ! cell component localization phenotype
property_value: prefLabel "transport phenotype" xsd:string
[Term]
id: CMPO:0000042
name: increased cell component number phenotype
def: "An increased number of specified cellular components relative to normal" []
subset: cmpo
is_a: CMPO:0000008 ! cell component number phenotype
property_value: prefLabel "increased cell component number" xsd:string
[Term]
id: CMPO:0000043
name: decreased cell component number phenotype
def: "A decrease in number of specified cellular components relative to normal" []
subset: cmpo
is_a: CMPO:0000008 ! cell component number phenotype
property_value: prefLabel "decreased cell component number" xsd:string
[Term]
id: CMPO:0000047
name: apoptotic DNA fragmentation phenotype
def: "A phenotype observation where the cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." []
subset: cmpo
synonym: "apoptotic DNA" BROAD []
is_a: CMPO:0000037 ! metabolic process phenotype
property_value: prefLabel "apoptotic DNA fragmentation" xsd:string
[Term]
id: CMPO:0000048
name: apoptotic cell shape phenotype
def: "A phenotype observation at the level of the cell shape where the cell is apoptotic" []
comment: dispersed outline with blobby protrusions
subset: cmpo
is_a: CMPO:0000005 ! cell morphology phenotype
is_a: CMPO:0000012 ! cell component structure phenotype
property_value: prefLabel "apoptotic cell shape" xsd:string
[Term]
id: CMPO:0000049
name: aggregated cells in population
def: "Groups of cells gathered or tending to gather into a mass or whole." []
subset: cmpo
synonym: "aggregated cells" EXACT []
synonym: "cell aggregates" EXACT []
synonym: "cell islands" EXACT []
synonym: "clustered cells" EXACT []
is_a: CMPO:0000002 ! cell population phenotype
property_value: prefLabel "aggregated cells in population" xsd:string
[Term]
id: CMPO:0000050
name: altered cell number in population
def: "Number of cells in a population phenotype" []
subset: cmpo
is_a: CMPO:0000002 ! cell population phenotype
property_value: prefLabel "cell number in population" xsd:string
[Term]
id: CMPO:0000051
name: increased cell numbers
def: "The population has an increased number of cells with respect to normal" []
subset: cmpo
is_a: CMPO:0000050 ! altered cell number in population
property_value: prefLabel "increased cell numbers" xsd:string
[Term]
id: CMPO:0000052
name: decreased cell numbers
def: "The population has a decreased number of cells with respect to normal" []
subset: cmpo
synonym: "decreased cells" EXACT []
synonym: "fewer cells" EXACT []
synonym: "less cells" EXACT []
synonym: "reduced cell numbers" EXACT []
is_a: CMPO:0000050 ! altered cell number in population
property_value: prefLabel "decreased cell numbers" xsd:string
[Term]
id: CMPO:0000053
name: more cells in S
def: "increased number of cells in S phase mitosis" []
subset: cmpo
is_a: CMPO:0000051 ! increased cell numbers
[Term]
id: CMPO:0000054
name: cell population phenotype by process
def: "A population of cells where a specifcied biological process is occuring or is observed. " []
subset: cmpo
is_a: CMPO:0000002 ! cell population phenotype
property_value: prefLabel "cell population process" xsd:string
[Term]
id: CMPO:0000055
name: more cells in G1
def: "increased cell numbers in G1" []
subset: cmpo
is_a: CMPO:0000051 ! increased cell numbers
[Term]
id: CMPO:0000056
name: more cells in G2M
def: "increased number of cells in G2M" []
subset: cmpo
synonym: "increased mitotic index" EXACT []
is_a: CMPO:0000051 ! increased cell numbers
[Term]
id: CMPO:0000057
name: fewer cells in G1
def: "decreased number of cells in G1 phase" []
subset: cmpo
synonym: "less cells in G1" EXACT []
is_a: CMPO:0000052 ! decreased cell numbers
[Term]
id: CMPO:0000058
name: fewer cells in G2M
def: "decreased number of cells in G2M phase" []
subset: cmpo
synonym: "decreased mitotic index" EXACT []
synonym: "less cells in G2M" EXACT []
is_a: CMPO:0000052 ! decreased cell numbers
[Term]
id: CMPO:0000059
name: fewer cells in S
def: "decreased number of cells in S phase" []
subset: cmpo
synonym: "decreased number of cells in S" EXACT []
synonym: "less cells in S" EXACT []
is_a: CMPO:0000052 ! decreased cell numbers
[Term]
id: CMPO:0000063
name: decreased number of focal adhesion phenotype
def: "A phenotype observation at the level of focal adhesions where the components number has decreased. " []
subset: cmpo
synonym: "decreased focal adhesion abundance" EXACT []
is_a: CMPO:0000043 ! decreased cell component number phenotype
property_value: prefLabel "decreased number of focal adhesion" xsd:string
[Term]
id: CMPO:0000064
name: centrally located focal adhesion phenotype
def: "A phenotype observation where the focal adhesion is located in a position equidistant from the edges of the cell" []
subset: cmpo
is_a: CMPO:0000065 ! cell component position phenotype
property_value: IAO:0000119 PMID:19667130 xsd:string
property_value: prefLabel "centrally located focal adhesion" xsd:string
[Term]
id: CMPO:0000065
name: cell component position phenotype
def: "A phenotype observation at the level of a cellular component relating to the components position in the cell" []
subset: cmpo
is_a: CMPO:0000259 ! cellular component phenotype
property_value: prefLabel "cell component position" xsd:string
[Term]
id: CMPO:0000066
name: peripheral focal adhesion phenotype
def: "A phenotype observation where the focal adhesions's position is at the edge or boundary of a related entity." []
subset: cmpo
is_a: CMPO:0000065 ! cell component position phenotype
property_value: IAO:0000119 PMID:19667130 xsd:string
property_value: prefLabel "peripheral focal adhesion" xsd:string
[Term]
id: CMPO:0000067
name: decreased number of filopodia phenotype
def: "A phenotype observation at the level of filopodia where the components number has decreased. " []
subset: cmpo
synonym: "fewer filopodia" EXACT []
is_a: CMPO:0000074 ! decreased number of cell projections phenotype
property_value: prefLabel "decreased number of filopodia" xsd:string
[Term]
id: CMPO:0000068
name: decreased number of microtubules phenotype
def: "A phenotype observation at the level of microtubules where the components number has decreased. " []
subset: cmpo
synonym: "fewer microtubules" EXACT []
is_a: CMPO:0000043 ! decreased cell component number phenotype
property_value: prefLabel "decreased number of microtubules" xsd:string
[Term]
id: CMPO:0000069
name: decreased number of dendritic branches phenotyope
def: "A phenotype observation at the level of dendritic branches where the components number has decreased. " []
subset: cmpo
is_a: CMPO:0000043 ! decreased cell component number phenotype
[Term]
id: CMPO:0000071
name: cell with projections
def: "Single cell with protrusions" []
subset: cmpo
synonym: "cell with protrusions" EXACT []
is_a: CMPO:0000005 ! cell morphology phenotype
property_value: IAO:0000119 PMID:20531400 xsd:string
[Term]
id: CMPO:0000072
name: increased number of cell projections phenotype
def: "An increase in number of any cell projection relative to normal" []
subset: cmpo
is_a: CMPO:0000042 ! increased cell component number phenotype
property_value: prefLabel "increased number of cell projections" xsd:string
[Term]
id: CMPO:0000073
name: more cells with projections
def: "increased number of cells in population with projections" []
subset: cmpo
is_a: CMPO:0000051 ! increased cell numbers
[Term]
id: CMPO:0000074
name: decreased number of cell projections phenotype
def: "A phenotype observation at the level of cell projections where the components number has decreased. " []
subset: cmpo
is_a: CMPO:0000043 ! decreased cell component number phenotype
property_value: prefLabel "decreased number of cell projections" xsd:string
[Term]
id: CMPO:0000075
name: fewer cells with projections
def: "decreased number of cells in population with projections" []
subset: cmpo
is_a: CMPO:0000052 ! decreased cell numbers
[Term]
id: CMPO:0000076
name: increased number of filopodia
def: "A phenotype observation at the level of filopodia where the components number has increased. " []
subset: cmpo
synonym: "more filopodia" EXACT []
is_a: CMPO:0000072 ! increased number of cell projections phenotype
[Term]
id: CMPO:0000077
name: elongated cell phenotype
def: "A phenotype observation at the level of the cell shape where the cell is elongated, with a length notably greater than its width" []
subset: cmpo
synonym: "bipolar cell" BROAD []
is_a: CMPO:0000005 ! cell morphology phenotype
is_a: CMPO:0000011 ! cell component shape phenotype
property_value: prefLabel "elongated cell" xsd:string
[Term]
id: CMPO:0000078
name: elongated cells in population
def: "Cells in population with a length notably greater than their width" []
subset: cmpo
is_a: CMPO:0000051 ! increased cell numbers
is_a: CMPO:0000163 ! cell population phenotype by morphology
property_value: IAO:0000119 "PMID:21893601; PMID:20531400" xsd:string
property_value: prefLabel "elongated cells in population" xsd:string
[Term]
id: CMPO:0000080
name: increased number of lamellipodia phenotype
def: "A phenotype observation at the level of lamellipodia where the components number has increased. " []
subset: cmpo
synonym: "lamellipodium phenotype" EXACT []
is_a: CMPO:0000072 ! increased number of cell projections phenotype
property_value: prefLabel "increased number of lamellipodia" xsd:string
[Term]
id: CMPO:0000081
name: decreased number of lamellipodia phenotype
def: "A phenotype observation at the level of lamellipodia where the components number has decreased. " []
subset: cmpo
is_a: CMPO:0000074 ! decreased number of cell projections phenotype
property_value: prefLabel "decreased number of lamellipodia" xsd:string
[Term]
id: CMPO:0000083
name: more lamellipodia cells
def: "increased lamellipodia cells in population phenotype" []
subset: cmpo
is_a: CMPO:0000073 ! more cells with projections
[Term]
id: CMPO:0000084
name: fewer lamellipodia cells
def: "decreased lamellipodia cells in population phenotype" []
subset: cmpo
is_a: CMPO:0000075 ! fewer cells with projections
[Term]
id: CMPO:0000085
name: cell ploidy phenotype
def: "A phenotype observation at the level of the whole cell relating to the cell's ploidy" []
subset: cmpo
is_a: CMPO:0000258 ! single cell phenotype
property_value: prefLabel "cell ploidy" xsd:string
[Term]
id: CMPO:0000086
name: polyploid cell phenotype
def: "A cell phenotype with more than two homologous sets of chromosomes." []
subset: cmpo
is_a: CMPO:0000085 ! cell ploidy phenotype
property_value: prefLabel "polyploid cell" xsd:string
[Term]
id: CMPO:0000087
name: S phase mitotic phenotype
def: "A phenotype observation at the level of athe S phase of the mitotic cell cycle" []
subset: cmpo
is_a: CMPO:0000090 ! cell cycle phase phenotype
is_a: CMPO:0000194 ! mitotic process phenotype
property_value: prefLabel "S phase mitotic phenotype" xsd:string
[Term]
id: CMPO:0000088
name: G1 phase mitotic phenotype
def: "A phenotype observation at the level of a G1 phase of the mitotic cell cycle" []
subset: cmpo
is_a: CMPO:0000090 ! cell cycle phase phenotype
is_a: CMPO:0000194 ! mitotic process phenotype
property_value: prefLabel "G1 phase mitotic phenotype" xsd:string
[Term]
id: CMPO:0000089
name: G2/M transition phenotype
def: "A phenotype observation at the level of the G2/M transition of the mitotic cell cycle" []
subset: cmpo
is_a: CMPO:0000194 ! mitotic process phenotype
property_value: prefLabel "G2/M transition phenotype" xsd:string
[Term]
id: CMPO:0000090
name: cell cycle phase phenotype
def: "A phenotype observation at the level of a cell cycle phase" []
subset: cmpo
is_a: CMPO:0000007 ! cell process phenotype
property_value: prefLabel "cell cycle phase phenotype" xsd:string
[Term]
id: CMPO:0000091
name: more polyploid cells
def: "increased number of polyploid cells in population" []
subset: cmpo
is_a: CMPO:0000051 ! increased cell numbers
[Term]
id: CMPO:0000092
name: increased number of focal adhesion phenotype
def: "A phenotype observation at the level of focal adhesions where the components number has increased. " []
subset: cmpo
synonym: "increased focal adhesion abundance" EXACT []
is_a: CMPO:0000042 ! increased cell component number phenotype
property_value: prefLabel "increased number of focal adhesion" xsd:string
[Term]
id: CMPO:0000093
name: increased number of nucleoli phenotype
def: "A phenotype observation at the level of nucleoli where the components number has increased. " []
subset: cmpo
is_a: CMPO:0000042 ! increased cell component number phenotype
property_value: prefLabel "increased number of nucleoli" xsd:string
[Term]
id: CMPO:0000094
name: decreased number of nucleoli phenotype
def: "A phenotype observation at the level of nucleoli where the components number has decreased. " []
subset: cmpo
is_a: CMPO:0000043 ! decreased cell component number phenotype
property_value: prefLabel "decreased number of nucleoli" xsd:string
[Term]
id: CMPO:0000095
name: more cells with decreased number of nucleoli
def: "more cells with decreased number of nucleoli" []
subset: cmpo
is_a: CMPO:0000051 ! increased cell numbers
[Term]
id: CMPO:0000096
name: more cells with increased number of nucleoli
def: "increased number of nucleoli in population phenotype" []
subset: cmpo
is_a: CMPO:0000051 ! increased cell numbers
[Term]
id: CMPO:0000097
name: increased number of microtubules phenotype
def: "A phenotype observation at the level of microtubules where the components number has increased. " []
subset: cmpo
synonym: "more microtubules" EXACT []
is_a: CMPO:0000042 ! increased cell component number phenotype
property_value: prefLabel "increased number of microtubules" xsd:string
[Term]
id: CMPO:0000102
name: phagosomes phenotype
def: "A phenotype observation at the level of the phagosomes, a membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis." []
subset: cmpo
synonym: "phagosomes present phenotype" EXACT []
is_a: CMPO:0000259 ! cellular component phenotype
property_value: prefLabel "phagosomes" xsd:string
[Term]
id: CMPO:0000103
name: phagosomes absent phenotype
def: "A phenotype observation where phagosomes are absent" []
subset: cmpo
is_a: CMPO:0000102 ! phagosomes phenotype
is_a: CMPO:0000159 ! absence of cellular component phenotype
property_value: prefLabel "phagosomes absent" xsd:string
[Term]
id: CMPO:0000104
name: actin filament phenotype
def: "A phenotype observation at the level of the actin filaments, a filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells." []
subset: cmpo
is_a: CMPO:0000020 ! cytoskeletal phenotype
property_value: prefLabel "actin filament phenotype" xsd:string
[Term]
id: CMPO:0000105
name: increased number of actin filament phenotype
def: "A phenotype observation at the level of actin filaments where the components number has increased. " []
subset: cmpo
synonym: "actin fiber cells" EXACT []
synonym: "more actin" EXACT []
synonym: "more total actin" EXACT []
is_a: CMPO:0000042 ! increased cell component number phenotype
is_a: CMPO:0000104 ! actin filament phenotype
property_value: IAO:0000119 "PMID: 21893601" xsd:string
property_value: IAO:0000119 PMID:20531400 xsd:string
property_value: prefLabel "increased number of actin filament" xsd:string
[Term]
id: CMPO:0000106
name: decreased number of actin filament phenotype
def: "A phenotype observation at the level of actin filaments where the components number has decreased. " []
subset: cmpo
synonym: "less actin" EXACT []
synonym: "less total actin" EXACT []
is_a: CMPO:0000043 ! decreased cell component number phenotype
is_a: CMPO:0000104 ! actin filament phenotype
property_value: IAO:0000119 "PMID: 21893601" xsd:string
property_value: prefLabel "decreased number of actin filament" xsd:string
[Term]
id: CMPO:0000107
name: more actin filament cells
def: "increased number of actin filament cells in population" []
subset: cmpo
is_a: CMPO:0000051 ! increased cell numbers
[Term]
id: CMPO:0000108
name: fewer actin filament cells
def: "decreased number of actin filament phenotypes in population" []
subset: cmpo
synonym: "decreased number of actin filament cells" EXACT []
is_a: CMPO:0000052 ! decreased cell numbers
[Term]
id: CMPO:0000109
name: centered cytoskeleton phenotype
def: "A phenotype observation where the cytoskeleton is located in a position equidistant from the edges of the cell" []
subset: cmpo
is_a: CMPO:0000020 ! cytoskeletal phenotype
is_a: CMPO:0000065 ! cell component position phenotype
property_value: prefLabel "centered cytoskeleton" xsd:string
[Term]
id: CMPO:0000110
name: centered nucleus phenotype
def: "A phenotype observation where the nucleus is located in a position equidistant from the edges of the cell" []
subset: cmpo
is_a: CMPO:0000024 ! nuclear phenotype
is_a: CMPO:0000065 ! cell component position phenotype
property_value: prefLabel "centered nucleus" xsd:string
[Term]
id: CMPO:0000111
name: dispersed nucleus phenotype
def: "A phenotype observation where the nucleus is distributed or spread over a considerable extent." []
subset: cmpo
is_a: CMPO:0000024 ! nuclear phenotype
is_a: CMPO:0000065 ! cell component position phenotype
property_value: prefLabel "dispersed nucleus" xsd:string
[Term]
id: CMPO:0000112
name: apoptopic nucleus phenotype
def: "A phenotype observation at the level of nucleus consisting of blebbing of the nucleus and DNA fragmentation due to the cell undergoing a specific form of programmed cell death termed apoptosis." []
subset: cmpo
is_a: CMPO:0000012 ! cell component structure phenotype
is_a: CMPO:0000249 ! nuclear morphology phenotype
property_value: prefLabel "apoptopic nucleus" xsd:string
[Term]
id: CMPO:0000113
name: deformed nucleus
def: "A phenotype observation where the nucleus is distorted in form" []
subset: cmpo
is_a: CMPO:0000249 ! nuclear morphology phenotype
[Term]
id: CMPO:0000114
name: peripheral nucleus phenotype
def: "A phenotype observation where the nucleus's position is at the edge or boundary of a related entity." []
subset: cmpo
is_a: CMPO:0000024 ! nuclear phenotype
is_a: CMPO:0000065 ! cell component position phenotype
property_value: prefLabel "peripheral nucleus" xsd:string
[Term]
id: CMPO:0000115
name: peripheral cytoskeleton phenotype
def: "A phenotype observation where the cytoskeleton's position is at the edge or boundary of a related entity." []
subset: cmpo
is_a: CMPO:0000020 ! cytoskeletal phenotype
is_a: CMPO:0000065 ! cell component position phenotype
property_value: prefLabel "peripheral cytoskeleton" xsd:string
[Term]
id: CMPO:0000116
name: abnormal cell shape phenotype
def: "A phenotype observation at the level of the cell shape where the shape is abnormal" []
subset: cmpo
is_a: CMPO:0000005 ! cell morphology phenotype
is_a: CMPO:0000011 ! cell component shape phenotype
property_value: prefLabel "abnormal cell shape" xsd:string
[Term]
id: CMPO:0000117
name: bilobed nucleus phenotype
def: "A lobed quality inhering in a nucleus by virtue of the nucleus being divided into or having two lobes." []
subset: cmpo
synonym: "bilobed" BROAD []
is_a: CMPO:0000027 ! nucleus shape phenotype
property_value: prefLabel "bilobed nucleus" xsd:string
[Term]
id: CMPO:0000118
name: round cell phenotype
def: "A phenotype observation at the level of the cell shape where the cell is round" []
comment: not spreading cell
subset: cmpo
synonym: "circular cell" EXACT []
synonym: "low eccentricity cell" EXACT []
synonym: "spherical cell" EXACT []
is_a: CMPO:0000005 ! cell morphology phenotype
is_a: CMPO:0000011 ! cell component shape phenotype
property_value: IAO:0000119 PMID:21893601 xsd:string
property_value: prefLabel "round cell" xsd:string
[Term]
id: CMPO:0000119
name: elongated focal adhesion
def: "A phenotype observation of the length of the focal adhesion is notably higher than the width." []
subset: cmpo
synonym: "long focal adhesion" BROAD []
is_a: CMPO:0000011 ! cell component shape phenotype
[Term]
id: CMPO:0000120
name: elongated nucleus
def: "A phenotype observation of the length of the nucleus is notably higher than the width." []
subset: cmpo
synonym: "long nucleus" BROAD []
is_a: CMPO:0000027 ! nucleus shape phenotype
[Term]
id: CMPO:0000121
name: arrow shaped cell phenotype
def: "A phenotype observation at the level of the cell shape where the cell is arrow shaped, with a wide front and a sharp tail, displaying monopolar cell growth" []
subset: cmpo
synonym: "triangular shaped cell" EXACT []
is_a: CMPO:0000005 ! cell morphology phenotype
is_a: CMPO:0000011 ! cell component shape phenotype
[Term]
id: CMPO:0000122
name: triangular shaped cell phenotype
def: "A phenotype observation at the level of the cell shape where the cell has a triangular shape, with a wide front and a sharp tail, displaying cell motility" []
subset: cmpo
synonym: "arrow shaped cell" BROAD []
is_a: CMPO:0000005 ! cell morphology phenotype
is_a: CMPO:0000011 ! cell component shape phenotype
property_value: prefLabel "triangular shaped cell" xsd:string
[Term]
id: CMPO:0000123
name: round nucleus phenotype
def: "A phenotype observation where the shape of the nucleus has every part of the surface or the circumference equidistant from the center." []
subset: cmpo
synonym: "circular nucleus" EXACT []
synonym: "round nucleus" EXACT []
is_a: CMPO:0000027 ! nucleus shape phenotype
property_value: prefLabel "round nucleus" xsd:string
[Term]
id: CMPO:0000125
name: nuclear body phenotype
def: "A phenotype observation at the level of the nuclear body, an extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins." []
subset: cmpo
is_a: CMPO:0000024 ! nuclear phenotype
property_value: prefLabel "nuclear body" xsd:string
[Term]
id: CMPO:0000126
name: increased nuclear body size phenotype
def: "A phenotype observation where the nuclear body size is relatively high." []
subset: cmpo
is_a: CMPO:0000125 ! nuclear body phenotype
is_a: CMPO:0000186 ! increased cell component size phenotype
is_a: CMPO:0000249 ! nuclear morphology phenotype
property_value: IAO:0000119 PMID:22884692 xsd:string
property_value: prefLabel "increased nuclear body size" xsd:string
[Term]
id: CMPO:0000127
name: decreased nuclear body size phenotype
def: "A phenotype observation where the nuclear body size is relatively low." []
subset: cmpo
is_a: CMPO:0000125 ! nuclear body phenotype
is_a: CMPO:0000187 ! decreased cell component size phenotype
is_a: CMPO:0000249 ! nuclear morphology phenotype
property_value: IAO:0000119 PMID:22884692 xsd:string
property_value: prefLabel "decreased nuclear body size" xsd:string
[Term]
id: CMPO:0000128
name: increased cell size phenotype
def: "A phenotype observation at the level of the cell size where a cell is larger with respect to normal/wild-type" []
subset: cmpo
synonym: "big cell" EXACT []
synonym: "increased cell area" EXACT []
synonym: "large cell" EXACT []
is_a: CMPO:0000005 ! cell morphology phenotype
is_a: CMPO:0000186 ! increased cell component size phenotype
property_value: IAO:0000119 PMID:20531400 xsd:string
property_value: prefLabel "increased cell size" xsd:string
[Term]
id: CMPO:0000129
name: decreased cell size phenotype
def: "A phenotype observation at the level of the cell size where a cell is smaller with respect to normal/wild-type" []
subset: cmpo
synonym: "small cell" EXACT []
is_a: CMPO:0000005 ! cell morphology phenotype
is_a: CMPO:0000187 ! decreased cell component size phenotype
[Term]
id: CMPO:0000130
name: decreased golgi volume phenotype
def: "A phenotype observation at the level of the golgi where the golgi's volume has decreased. " []
subset: cmpo
is_a: CMPO:0000187 ! decreased cell component size phenotype
property_value: prefLabel "decreased golgi volume" xsd:string
[Term]
id: CMPO:0000131
name: increased golgi volume phenotype
def: "A phenotype observation at the level of the golgi where the golgi's volume has increased. " []
subset: cmpo
is_a: CMPO:0000186 ! increased cell component size phenotype
property_value: prefLabel "increased golgi volume" xsd:string
[Term]
id: CMPO:0000132
name: decreased cilium length phenotype
def: "A phenotype observation at the level of a cilium where the components length has decreased. " []
subset: cmpo
is_a: CMPO:0000187 ! decreased cell component size phenotype
is_a: CMPO:0000252 ! cilium morphology phenotype
property_value: prefLabel "decreased cilium length" xsd:string
[Term]
id: CMPO:0000133
name: increased cilium length phenotype
def: "A phenotype observation at the level of a cilium where the components length has increased. " []
subset: cmpo
is_a: CMPO:0000186 ! increased cell component size phenotype
is_a: CMPO:0000252 ! cilium morphology phenotype
property_value: prefLabel "increased cilium length" xsd:string
[Term]
id: CMPO:0000134
name: decreased size of focal adhesion phenotype
def: "A phenotype observation where the size of the focal adhesion has decreased. " []
subset: cmpo
is_a: CMPO:0000187 ! decreased cell component size phenotype
property_value: prefLabel "decreased size of focal adhesion" xsd:string
[Term]
id: CMPO:0000135
name: increased size of focal adhesion phenotype
def: "A phenotype observation where the size of the focal adhesion has increased. " []
subset: cmpo
is_a: CMPO:0000186 ! increased cell component size phenotype
property_value: prefLabel "increased size of focal adhesion" xsd:string
[Term]
id: CMPO:0000136
name: decreased focal adhesion area phenotype
def: "A phenotype observation where the area of the focal adhesion has decreased. " []